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GATE IO KR

HTTPS GATE.IO ACTIVE 1593909 4629BDE930E8232B5E2EF099DEB943AC

We are a young research group belonging to the LBBE lab of the School of Biotechnology at Jiangnan University. The group is led by Prof. Dr. Zhen Kang. Our work focuses on the biosynthesis of structure- or molecular weight-specified glycosaminoglycans by engineering industrial microorganisms, such as E. coli, C. glutamicum, B. subtilis, and P. pastoris. We also design synthetic regulatory elements applicable to these microorganisms.

Our research interests include:

  • Metabolic engineering of industrial microorganisms
  • Synthetic biology and regulatory element design
  • Biosynthesis of glycosaminoglycans
  • Development of novel biotechnology tools and methods

You can find more about our research on ResearchGate or PubMed.

We welcome undergraduate students and postdocs to join our group.

Our Research Team

BABY DOGECOIN GATEIO

As part of our research, we have developed several computational tools to assist in RNA design and analysis:

  • sslRNAD: A tool for designing small synthetic regulatory RNAs.
  • MS-DOS Designer: A platform for designing multi-stable RNA devices.
  • PrimerDesign: An automated tool for designing primers for various molecular biology applications.

These tools are freely available on this website for the scientific community to use and benefit from.

GATE.IO SUPPORTED COUNTRIES

  • Ruirui Xu, Weijao Zhang, Xintong Xi, et al. (2023). Engineering sulfonate group donor regeneration systems to boost biosynthesis of sulfated compounds. Nat Commun, 14(1):7297. DOI:10.1038/s41467-023-43195-1
  • Ruirui Xu, Yang Wang, Hao Huang, et al. (2021). Closed-Loop System Driven by ADP Phosphorylation from Pyrophosphate Affords Equimolar Transformation of ATP to 3′-Phosphoadenosine-5′-phosphosulfate ACS Catalysis, 11(16):10405-10415. DOI:10.1021/acscatal.1c02004
  • Yang Wang, Litao Hu, Hao Huang, et al. (2020). Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum Nat Commun, 11(1):3120. DOI: 10.1038/s41467-020-16962-7

For a complete list of our publications, please visit our PubMed page.